SAR408701 Versus Docetaxel in Previously Treated, Carcinoembryonic Antigen-related Cell Adhesion Molecule 5 (CEACAM5) Positive Metastatic Non-squamous Non-small Cell Lung Cancer Patients (CARMEN-LC03)

Studiedetails

Type carcinoma: NSCLC met mutatie
Stadium:
Mutatie: CAE-CAM5 (wordt in prescreening bepaald)
Lijn: 2e/3e
Site: Erasmus MC & Amphia
Contactgegevens:

long.oncologie@erasmusmc.nl
researchlongoncologie@amphia.nl
Website:

 Inclusiecriteria

– Histologically or cytologically proven diagnosis of non-squamous NSCLC metastatic disease
– Progressive disease during or after platinum-based chemotherapy (at least 2 cycles).
– Having progressive disease during or after one immune checkpoint inhibitor
– Participant with EGFR sensitizing mutation or BRAF mutation or ALK/ROS alterations must be able to demonstrate progression of the disease on approved treatments for these conditions
– (ECOG) performance status 0-1

 Exclusiecriteria

Meer studies

Een overzicht van alle lopende studies binnen het longkankernetwerk. Filter op type mutatie:

KontRASt-06

An open-label Phase II trial evaluating the activity and safety of JDQ443 single-agent as first-line treatment for patients with locally advanced or metastatic KRAS G12C-mutant non-small cell lung cancer (NSCLC) with a PD-L1 expression <1% or a PD-L1 expression ≥1% and an STK11 co-mutation