SAR408701 Versus Docetaxel in Previously Treated, Carcinoembryonic Antigen-related Cell Adhesion Molecule 5 (CEACAM5) Positive Metastatic Non-squamous Non-small Cell Lung Cancer Patients (CARMEN-LC03)


Type carcinoma: NSCLC met mutatie
Mutatie: CAE-CAM5 (wordt in prescreening bepaald)
Lijn: 2e/3e
Site: Erasmus MC & Amphia



– Histologically or cytologically proven diagnosis of non-squamous NSCLC metastatic disease
– Progressive disease during or after platinum-based chemotherapy (at least 2 cycles).
– Having progressive disease during or after one immune checkpoint inhibitor
– Participant with EGFR sensitizing mutation or BRAF mutation or ALK/ROS alterations must be able to demonstrate progression of the disease on approved treatments for these conditions
– (ECOG) performance status 0-1


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