Zimberelimab and Domvanalimab in Combination With Chemotherapy Versus Pembrolizumab With Chemotherapy in Patients With Untreated Metastatic Non-Small Cell Lung Cancer (STAR-121)
Studiedetails
Type carcinoma: | NSCLC zonder mutatie |
---|---|
Stadium: | IV |
Mutatie: | - |
Lijn: | 1e |
Site: | Erasmus MC & Amphia |
Contactgegevens: | long.oncologie@erasmusmc.nl |
Website: |
Inclusiecriteria
- Stadium IV NSCLC, Squamous and non-squamous
- Negative test results for (EGFR) and (ALK)
- Have not received prior systemic treatment for metastatic NSCLC. Participants who received adjuvant or neoadjuvant chemotherapy are eligible if the adjuvant/neoadjuvant chemotherapy was completed at least 12 months prior to the start of study treatment.
- One biopsies and fine needle aspirates are not suitable tissues
- ECOG PS score 0 or 1
Exclusiecriteria
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ImmunoSABR
stadium IV - 1ste, 2de of 3de lijn
GENMAB
2de lijn - stadium IV
EVOKE
2de lijns | Stadium III/IV
Entrectinib
Stadium IIIB-IV | Eerstelijns | ROS1 mutation
Ensure
Eerstelijn | Fase I
DeLLphi-304
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CUP/EAP/DAP/DRUP
Lijst van verschillende programma's
CARMEN-LC03
2e/3e lijns | Stadium III/IV